Detalhe da pesquisa
1.
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway.
Cell
; 148(1-2): 244-58, 2012 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22265415
2.
Metallaphotoredox-enabled deoxygenative arylation of alcohols.
Nature
; 598(7881): 451-456, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34464959
3.
Simvastatin in Critically Ill Patients with Covid-19.
N Engl J Med
; 389(25): 2341-2354, 2023 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37888913
4.
Lipophilic Statins Inhibit YAP Nuclear Localization, Coactivator Activity, and Migration in Response to Ligation of HLA Class I Molecules in Endothelial Cells: Role of YAP Multisite Phosphorylation.
J Immunol
; 210(8): 1134-1145, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36881871
5.
Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity.
Genes Dev
; 31(13): 1339-1353, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790158
6.
Polypill with or without Aspirin in Persons without Cardiovascular Disease.
N Engl J Med
; 384(3): 216-228, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33186492
7.
Elevated ferritin, mediated by IL-18 is associated with systemic inflammation and mortality in acute respiratory distress syndrome (ARDS).
Thorax
; 79(3): 227-235, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38148147
8.
Overcoming statin resistance in prostate cancer cells by targeting the 3-hydroxy-3-methylglutaryl-CoA-reductase.
Biochem Biophys Res Commun
; 710: 149841, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38588613
9.
Statins affect human iPSC-derived cardiomyocytes by interfering with mitochondrial function and intracellular acidification.
Basic Res Cardiol
; 119(2): 309-327, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38305903
10.
Simvastatin Differentially Modulates Glial Functions in Cultured Cortical and Hypothalamic Astrocytes Derived from Interferon α/ß Receptor Knockout mice.
Neurochem Res
; 49(3): 732-743, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38063948
11.
Overcoming Resistance in Prostate Cancer Therapy Using a DZ-Simvastatin Conjugate.
Mol Pharm
; 21(2): 873-882, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38229228
12.
Simvastatin restores pulmonary endothelial function in the setting of pulmonary over-circulation.
Nitric Oxide
; 142: 58-68, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38061411
13.
Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients.
PLoS Comput Biol
; 19(5): e1011050, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37146076
14.
Comparative retention and effectiveness of migraine preventive treatments: A nationwide registry-based cohort study.
Eur J Neurol
; 31(1): e16062, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37754544
15.
A systematic review of case series and clinical trials investigating systemic oral or injectable therapies for the treatment of vitiligo.
Skin Res Technol
; 30(3): e13642, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38454597
16.
Simvastatin Attenuates Cardiac Fibrosis under Pathophysiological Conditions of Heart Failure with Preserved Left Ventricular Ejection Fraction by Inhibiting TGF-ß Signaling.
Pharmacology
; 109(1): 43-51, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38016432
17.
Customizing biomimetic surface attributes of dendritic lipopeptide nanoplatforms for extended circulation.
Nanomedicine
; 56: 102726, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38052371
18.
Statins-Their Role in Bone Tissue Metabolism and Local Applications with Different Carriers.
Int J Mol Sci
; 25(4)2024 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38397055
19.
Anti-inflammatory potential of simvastatin and amfenac in ARPE-19 cells; insights in preventing re-detachment and proliferative vitreoretinopathy after rhegmatogenous retinal detachment surgery.
Int Ophthalmol
; 44(1): 158, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38530532
20.
Statins inhibit protein kinase D (PKD) activation in intestinal cells and prevent PKD1-induced growth of murine enteroids.
Am J Physiol Cell Physiol
; 324(4): C807-C820, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36779664